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Takeshi Kano Selected Research

lusutrombopag

2/2023Lusutrombopag for thrombocytopenia in Chinese patients with chronic liver disease undergoing invasive procedures.
2/2022Relationship between baseline clinical characteristics and efficacy of lusutrombopag in thrombocytopenic patients with chronic liver disease: post hoc analysis of two placebo-controlled phase 3 trials.
1/2022Pharmacokinetic Assessment and Treatment Effect of Lusutrombopag in Child-Pugh Class C Patients: Review of Patient Data from Two Clinical Studies and Post-Marketing Surveillance.
6/2021Bleeding events in lusutrombopag-treated thrombocytopenic patients.
4/2021Assessing the periprocedural magnitude of platelet count change in response to lusutrombopag.
12/2020Evaluation of drug-drug interaction of lusutrombopag, a thrombopoietin receptor agonist, via metabolic enzymes and transporters.
10/2020Is platelet monitoring during 7-day lusutrombopag treatment necessary in chronic liver disease patients with thrombocytopenia undergoing planned invasive procedures? A phase IIIb open-label study.
10/2020Lusutrombopag Is Safe and Efficacious for Treatment of Thrombocytopenia in Patients With and Without Hepatocellular Carcinoma.
11/2019Pharmacokinetic/Pharmacodynamic Modelling and Simulation of Lusutrombopag, a Novel Thrombopoietin Receptor Agonist, for the Treatment of Thrombocytopenia in Patients with Chronic Liver Disease Undergoing Invasive Procedures.
10/2019Lusutrombopag for the Treatment of Thrombocytopenia in Patients With Chronic Liver Disease Undergoing Invasive Procedures (L-PLUS 2).
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Takeshi Kano Research Topics

Disease

10Liver Diseases (Liver Disease)
02/2023 - 01/2019
9Thrombocytopenia (Thrombopenia)
02/2023 - 01/2019
6Hemorrhage
02/2023 - 10/2019
2Thrombosis (Thrombus)
10/2020 - 10/2020
1Hemangioma (Angioma)
07/2021
1Breast Neoplasms (Breast Cancer)
12/2020
1Hepatocellular Carcinoma (Hepatoma)
10/2020
1Body Weight (Weight, Body)
11/2019
1Liver Neoplasms (Liver Cancer)
02/2019
1Drug-Related Side Effects and Adverse Reactions
01/2019

Drug/Important Bio-Agent (IBA)

12lusutrombopagIBA
02/2023 - 01/2019
5Thrombopoietin ReceptorsIBA
02/2022 - 11/2019
1Capsules (Microcapsules)IBA
07/2021
1Member 1 Subfamily B ATP Binding Cassette TransporterIBA
12/2020
1Cytochrome P-450 Enzyme System (Cytochrome P450)IBA
12/2020
1Proteins (Proteins, Gene)FDA Link
12/2020
1Cyclosporine (Ciclosporin)FDA LinkGeneric
12/2020
12,5-dichloro-4-bromophenol (B 2)IBA
10/2020
1Thrombopoietin (c-mpl Ligand)IBA
10/2019

Therapy/Procedure

6Platelet Transfusion (Blood Platelet Transfusions)
02/2023 - 01/2019
3Therapeutics
02/2023 - 10/2019
1Laparotomy
07/2021
1Radiofrequency Ablation
02/2019